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What is CMV?

And what does it mean for me or my loved one after a transplant?

The basics:

CMV is one of the most common post-transplant infections. Most people have been exposed to it before, but the immune system keeps it in check. When the immune system is weakened, it may not be strong enough to hold back CMV. Luckily, there are treatments that can help fight CMV.

As someone who had a transplant, the medicines you may have been given could weaken your immune system and leave you vulnerable to CMV infection and disease.

If you have active CMV, your doctor might give you antiviral medicines to manage it. Your doctor will keep track of your progress by testing the level of virus in your blood as needed.

What are Refractory CMV
and Resistant CMV?

Refractory CMV is diagnosed when a lab test shows the levels of CMV virus in the blood has not adequately decreased after 2 weeks of treatment.

In addition, when a lab test shows a type of CMV with a gene mutation known to prevent the medication from working, that is considered resistant CMV.

If you have refractory or resistant CMV, your transplant team may then give you a different antiviral medicine in order to help fight the infection.

CMV and my transplant

choose yours

Remember: you might have questions or concerns during this process.
If you do, be sure to always talk to your transplant team.

Need help talking about
your treatment plan?

Explore Tips for Talking
with your Transplant Team

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Important Safety Information

Before taking LIVTENCITY, tell your healthcare provider about all your medical conditions, including if you:

  • are pregnant or plan to become pregnant. It is not known if LIVTENCITY will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if LIVTENCITY passes into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with LIVTENCITY.

Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. LIVTENCITY may affect the way other medicines work, and other medicines may affect how LIVTENCITY works and cause serious side effects.

Especially tell your healthcare provider if you take a seizure (anticonvulsant) medicine.

  • Do not start a new medicine without telling your healthcare provider. Your healthcare provider will tell you if it is safe to take LIVTENCITY with other medicines.

What are the possible side effects of LIVTENCITY?

The most common side effects of LIVTENCITY include:

  • changes in taste
  • nausea
  • diarrhea
  • vomiting
  • tiredness

These are not all the possible side effects of LIVTENCITY. Call your doctor for medical advice about side effects.

For additional safety information, click for Patient Information and discuss with your HCP.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.


LIVTENCITY is a prescription medicine used to treat cytomegalovirus (CMV) infection and disease in adults and children 12 years of age and older weighing at least 77 pounds (35 kg) who have received a transplant, when their infection or disease does not respond to treatment with the medicines ganciclovir, valganciclovir, cidofovir or foscarnet. It is not known if LIVTENCITY is safe and effective in children under 12 years of age.

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